Metformin (SR) 500 mg + Voglibose 0.2 mg + Glimepiride 1 mg Bilayered Tablet is a triple fixed-dose combination for type 2 diabetes that integrates sustained-release metformin (hepatic gluconeogenesis suppression), glimepiride (pancreatic insulin secretion stimulation), and voglibose (alpha-glucosidase inhibition to blunt postprandial glucose spikes).
This synergistic bilayer formulation provides comprehensive glycemic control (HbA1c 2.0-2.5%) targeting fasting, postprandial glucose, and glycemic variability, particularly effective in Indian patients with high postprandial excursions; CDSCO-approved FDC reduces pill burden while managing the "glycemic hexad."
Adults: 1 tablet once daily before meals; side effects include hypoglycemia (10-15%), flatulence/abdominal discomfort (voglibose-related), GI upset (less with SR), weight-neutral; contraindicated in DKA, eGFR<30 mL/min; monitor HbA1c quarterly, renal function.